![]() Journal of Radiation Research, 57, 412-417. (2016) Radiation therapy for localized duodenal low-grade follicular lymphoma. Harada, A., Oguchi, M., Terui, Y., Takeuchi, K., Igarashi, M., Kozuka, T., Harada, K., Uno, T. (2014) Early lymphoid lesions: conceptual, diagnostic and clinical challenges. Ganapathi, K.A., Pittaluga, S., Odejide, O.O., Freedman, A.S. American Journal of Pathology, 162, 105-113. (2003) Primary follicular lymphoma of the small intestine: alpha4beta7 expression and immunoglobulin configuration suggest an origin from local antigen-experienced B cells. ![]() The Lancet Oncology, 15, 424-435.īende, R.J., Smit, L.A., Bossenbroek, J.G., Aarts, W.M., Spaargaren, M., de Leval, L., Boeckxstaens, G.E., Pals, S.T. (2014) Rituximab versus a watch-and-wait approach in patients with advanced-stage, asymptomatic, non-bulky follicular lymphoma: an open-label randomised phase 3 trial. Medicine, 93, e165.Īrdeshna, K.M., Qian, W., Smith, P., Braganca, N., Lowry, L., Patrick, P., Warden, J., Stevens, L., Pocock, C.F., Miall, F., Cunningham, D., Davies, J., Jack, A., Stephens, R., Walewski, J., Ferhanoglu, B., Bradstock, K. Of, relating to, or manifesting behavior that is habitual, maladaptive, and compulsive. (2014) A case report of the histologic transformation of primary follicular lymphoma of the duodenum. © 2019 British Society for Haematology and John Wiley & Sons Ltd.Īkiyama, S., Izutsu, K., Ota, Y., Imamura, T., Ogawa, O., Wake, A. IgA expression duodenal-type follicular lymphoma follicular lymphoma haematopathology watch and wait. In this review, we summarise current pathological data and treatment studies in DFL. ![]() Treatment options include a watch and wait strategy, rituximab monotherapy and radiotherapy. Clinical series published vary between 20-63 patients with an estimated overall survival between 92-100% and a median follow-up ranging between 20 and 107 months. Markers associated with inflammation have suggested that the microenvironment plays a likely role in the pathogenesis of DFL and its low progression rate. The molecular landscape of DFL is similar to the classical nodal presentation of FL, although studies using gene expression profiling demonstrate a close relation with MALT lymphomas. Consensus and accurate diagnosis of clinically suspected VaD relies on wide-ranging clinical, neuropsychological and neuroimaging measures in life but more importantly pathological confirmation. Specific pathological features, such as a dendritic cell meshwork, low expression of CD10 and upregulation of activation-induced cytidine deaminase can help the diagnosis. Vascular dementia (VaD) is widely recognised as the second most common type of dementia. In general, patients tend to have mild symptoms and do not require therapy, comparable with other forms of low-tumour burden asymptomatic FL. Duodenal-type follicular lymphoma (DFL) is a newly recognised variant of follicular lymphoma (FL), although little is known about its biology and clinical evolution.
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